Intrauterine insemination (IUI) is a commonly used procedure that involves processing or “washing” of a semen sample to help to concentrate the live, motile sperm and place it into the uterine cavity, thereby bypassing the cervical mucous and getting the sperm closer to the fallopian tubes where fertilization can take place.
The indications for this procedure include, but may not be limited to, fertility issues related to “male-factor” (low motility, low sperm count, or abnormal sperm shape), and “unexplained infertility” (fertility issues that can’t be specifically diagnosed). Another indication would be the need for donor sperm.
The insemination must be performed on the approximate date of ovulation. IUI is often used in combination with oral ovulation induction agents (Clomid or Femara) or injectable gonadotropins (Gonal-F, Follistim, or Menopur).